Found 34 of ic50 for ACYL-PROTEIN THIOESTERASE 2having polymerids = 5272,50000796,8706,8710,8709,8708,8707,8704,8705,8711 and
complexids = 50000697
Affinity DataIC50: 12nMAssay Description:Inhibition of FP-Rh binding to APT-1/2 in mouse brain cytosolic fraction preincubated for 1 hr followed by FP-Rh addition and measured after 1 hr by ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of APT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of FP-Rh binding to APT-1/2 in mouse brain cytosolic fraction preincubated for 1 hr followed by FP-Rh addition and measured after 1 hr by ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human APT2More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of APT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human APT2More data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 418nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of FP-Rh binding to APT-1/2 in mouse brain cytosolic fraction preincubated for 1 hr followed by FP-Rh addition and measured after 1 hr by ...More data for this Ligand-Target Pair
Affinity DataIC50: 529nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nM Kd: 160nMT: 2°CAssay Description:Varying amounts of enzyme were diluted in PBS supplemented with 0.5 g/L pluronic F127 and incubated with 500 nM ML349-FL for 30 minutes at room tempe...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nM Kd: 240nMT: 2°CAssay Description:Varying amounts of enzyme were diluted in PBS supplemented with 0.5 g/L pluronic F127 and incubated with 500 nM ML349-FL for 30 minutes at room tempe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 3.55E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 4.18E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nM Kd: 2.60E+3nMT: 2°CAssay Description:Varying amounts of enzyme were diluted in PBS supplemented with 0.5 g/L pluronic F127 and incubated with 500 nM ML349-FL for 30 minutes at room tempe...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human APT2More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nM Kd: 5.20E+3nMT: 2°CAssay Description:Varying amounts of enzyme were diluted in PBS supplemented with 0.5 g/L pluronic F127 and incubated with 500 nM ML349-FL for 30 minutes at room tempe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nM Kd: >1.00E+4nMT: 2°CAssay Description:Varying amounts of enzyme were diluted in PBS supplemented with 0.5 g/L pluronic F127 and incubated with 500 nM ML349-FL for 30 minutes at room tempe...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nM Kd: >1.00E+4nMT: 2°CAssay Description:Varying amounts of enzyme were diluted in PBS supplemented with 0.5 g/L pluronic F127 and incubated with 500 nM ML349-FL for 30 minutes at room tempe...More data for this Ligand-Target Pair
